GPER Activation Inhibits Cancer Cell Mechanotransduction and Basement Membrane Invasion via RhoA

The invasive properties of cancer cells are intimately linked to their mechanical phenotype, which can be regulated by intracellular biochemical signalling. Cell contractility, induced by mechanotransduction of a stiff fibrotic matrix, and the epithelial–mesenchymal transition (EMT) promote invasion...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Rice, Alistair, Cortes, Ernesto, Lachowski, Dariusz, Oertle, Philipp, Matellan, Carlos, Thorpe, Stephen D., Ghose, Ritobrata, Wang, Haiyun, Lee, David A., Plodinec, Marija, del Río Hernández, Armando E.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073197/
https://ncbi.nlm.nih.gov/pubmed/31991740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020289
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