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Mechanical unfolding reveals stable 3-helix intermediates in talin and α-catenin
Mechanical stability is a key feature in the regulation of structural scaffolding proteins and their functions. Despite the abundance of α-helical structures among the human proteome and their undisputed importance in health and disease, the fundamental principles of their behavior under mechanical...
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| Опубликовано в: : | PLoS Comput Biol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940241/ https://ncbi.nlm.nih.gov/pubmed/29698481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006126 |
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