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Mechanical unfolding reveals stable 3-helix intermediates in talin and α-catenin
Mechanical stability is a key feature in the regulation of structural scaffolding proteins and their functions. Despite the abundance of α-helical structures among the human proteome and their undisputed importance in health and disease, the fundamental principles of their behavior under mechanical...
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| Publicat a: | PLoS Comput Biol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940241/ https://ncbi.nlm.nih.gov/pubmed/29698481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006126 |
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