Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease. Although rigorous efforts identified the presence of ‘cancer stem cells (CSCs)’ in PDAC and molecular markers for them, stem cell dynamics in vivo have not been clearly demonstrated. Here we focused on Doublecortin-like kinase 1 (Dclk...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Maruno, Takahisa, Fukuda, Akihisa, Goto, Norihiro, Tsuda, Motoyuki, Ikuta, Kozo, Hiramatsu, Yukiko, Ogawa, Satoshi, Nakanishi, Yuki, Yamaga, Yuichi, Yoshioka, Takuto, Takaori, Kyoichi, Uemoto, Shinji, Saur, Dieter, Chiba, Tsutomu, Seno, Hiroshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2021
Konular:
Cancer Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7800378/
https://ncbi.nlm.nih.gov/pubmed/33393460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55117
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