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Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease. Although rigorous efforts identified the presence of ‘cancer stem cells (CSCs)’ in PDAC and molecular markers for them, stem cell dynamics in vivo have not been clearly demonstrated. Here we focused on Doublecortin-like kinase 1 (Dclk...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7800378/ https://ncbi.nlm.nih.gov/pubmed/33393460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55117 |
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