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Epithelial EP4 plays an essential role in maintaining homeostasis in colon

Colonic epithelial cells comprise the mucosal barrier, and their dysfunction promotes microbial invasion from the gut lumen and induces the development of intestinal inflammation. The EP4 receptor is known to mediate the protective effect of prostaglandin (PG) E(2) in the gastrointestinal tract; how...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Matsumoto, Yoshihide, Nakanishi, Yuki, Yoshioka, Takuto, Yamaga, Yuichi, Masuda, Tomonori, Fukunaga, Yuichi, Sono, Makoto, Yoshikawa, Takaaki, Nagao, Munemasa, Araki, Osamu, Ogawa, Satoshi, Goto, Norihiro, Hiramatsu, Yukiko, Breyer, Richard M., Fukuda, Akihisa, Seno, Hiroshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811535/
https://ncbi.nlm.nih.gov/pubmed/31645712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51639-2
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