Epithelial EP4 plays an essential role in maintaining homeostasis in colon

Colonic epithelial cells comprise the mucosal barrier, and their dysfunction promotes microbial invasion from the gut lumen and induces the development of intestinal inflammation. The EP4 receptor is known to mediate the protective effect of prostaglandin (PG) E(2) in the gastrointestinal tract; how...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Matsumoto, Yoshihide, Nakanishi, Yuki, Yoshioka, Takuto, Yamaga, Yuichi, Masuda, Tomonori, Fukunaga, Yuichi, Sono, Makoto, Yoshikawa, Takaaki, Nagao, Munemasa, Araki, Osamu, Ogawa, Satoshi, Goto, Norihiro, Hiramatsu, Yukiko, Breyer, Richard M., Fukuda, Akihisa, Seno, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811535/
https://ncbi.nlm.nih.gov/pubmed/31645712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51639-2
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