Epithelial EP4 plays an essential role in maintaining homeostasis in colon

Colonic epithelial cells comprise the mucosal barrier, and their dysfunction promotes microbial invasion from the gut lumen and induces the development of intestinal inflammation. The EP4 receptor is known to mediate the protective effect of prostaglandin (PG) E(2) in the gastrointestinal tract; how...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matsumoto, Yoshihide, Nakanishi, Yuki, Yoshioka, Takuto, Yamaga, Yuichi, Masuda, Tomonori, Fukunaga, Yuichi, Sono, Makoto, Yoshikawa, Takaaki, Nagao, Munemasa, Araki, Osamu, Ogawa, Satoshi, Goto, Norihiro, Hiramatsu, Yukiko, Breyer, Richard M., Fukuda, Akihisa, Seno, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811535/
https://ncbi.nlm.nih.gov/pubmed/31645712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51639-2
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