Dual Angiotensin Receptor-Neprilysin Inhibition With Sacubitril/Valsartan Attenuates Systolic Dysfunction in Experimental Doxorubicin-Induced Cardiotoxicity

BACKGROUND: Doxorubicin (DOX) induces cardiotoxicity in part by activation of matrix metalloproteinases (MMPs). Sacubitril/valsartan (Sac/Val) exerts additive cardioprotective actions over renin-angiotensin-aldosterone inhibitors in preclinical models of myocardial infarction and in heart failure pa...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:JACC CardioOncol
Autors principals: Boutagy, Nabil E., Feher, Attila, Pfau, Daniel, Liu, Zhao, Guerrera, Nicole M., Freeburg, Lisa A., Womack, Sydney J., Hoenes, Abigail C., Zeiss, Caroline, Young, Lawrence H., Spinale, Francis G., Sinusas, Albert J.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7799406/
https://ncbi.nlm.nih.gov/pubmed/33437965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaccao.2020.09.007
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars