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Chimeric antigen receptor T-cell immunotherapy in breast cancer: development and challenges

Chimeric antigen receptor (CAR) T-cell therapy is an innovative form of immunotherapy wherein autologous T-cells are genetically modified to express chimeric receptors encoding an antigen-specific single-chain variable fragment and costimulatory molecules. Moreover, CAR T-cell therapy can only work...

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Bibliographic Details
Published in:J Cancer
Main Authors: Toulouie, Sara, Johanning, Gary, Shi, Yihui
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797648/
https://ncbi.nlm.nih.gov/pubmed/33442419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.54095
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