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Chimeric antigen receptor for adoptive immunotherapy of cancer: latest research and future prospects

Chimeric antigen receptors (CARs) are recombinant receptors that combine the specificity of an antigen-specific antibody with the T-cell’s activating functions. Initial clinical trials of genetically engineered CAR T cells have significantly raised the profile of T cell therapy, and great efforts ha...

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Bibliografiske detaljer
Main Authors: Shi, Huan, Sun, Meili, Liu, Lin, Wang, Zhehai
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177696/
https://ncbi.nlm.nih.gov/pubmed/25241075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-219
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