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Crohn’s Disease Pathobiont Adherent-Invasive E coli Disrupts Epithelial Mitochondrial Networks With Implications for Gut Permeability

BACKGROUND & AIMS: Adherent-invasive Escherichia coli are implicated in inflammatory bowel disease, and mitochondrial dysfunction has been observed in biopsy specimens from patients with inflammatory bowel disease. As a novel aspect of adherent-invasive E coli–epithelial interaction, we hypothes...

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Pubblicato in:Cell Mol Gastroenterol Hepatol
Autori principali: Mancini, Nicole L., Rajeev, Sruthi, Jayme, Timothy S., Wang, Arthur, Keita, Åsa V., Workentine, Matthew L., Hamed, Samira, Söderholm, Johan D., Lopes, Fernando, Shutt, Timothy E., Shearer, Jane, McKay, Derek M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797367/
https://ncbi.nlm.nih.gov/pubmed/32992049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.09.013
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