Human interleukin-4–treated regulatory macrophages promote epithelial wound healing and reduce colitis in a mouse model

Murine alternatively activated macrophages can exert anti-inflammatory effects. We sought to determine if IL-4–treated human macrophages [i.e., hM(IL4)] would promote epithelial wound repair and can serve as a cell transfer treatment for inflammatory bowel disease (IBD). Blood monocytes from healthy...

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Bibliographic Details
Published in:Sci Adv
Main Authors: Jayme, Timothy S., Leung, Gabriella, Wang, Arthur, Workentine, Matthew L., Rajeev, Sruthi, Shute, Adam, Callejas, Blanca E., Mancini, Nicole, Beck, Paul L., Panaccione, Remo, McKay, Derek M.
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2020
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274799/
https://ncbi.nlm.nih.gov/pubmed/32548267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba4376
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