A155 THE IMMUNOMODULATOR, LEFLUNOMIDE, REDUCES MITOCHONDRIAL FRAGMENTATION CAUSED BY ADHERENT–INVASIVE E. COLI AND PERSISTENCE OF THE PATHOBIONT WITHIN ENTERIC EPITHELIA

BACKGROUND: Mitochondria can exist as a dynamic network that constantly remodels via the processes of fission and fusion (mitochondrial dynamics) to meet cellular energy demands and allow recycling of damaged mitochondria. Mitochondrial dysfunction can occur in inflammatory bowel disease. Adherent-i...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Mancini, N, Wang, A, McKay, D M, Shearer, J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512515/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz006.154
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