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Indomethacin-induced translocation of bacteria across enteric epithelia is reactive oxygen species-dependent and reduced by vitamin C

The enteric epithelium must absorb nutrients and water and act as a barrier to the entry of luminal material into the body; this barrier function is a key component of innate immunity. Nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy occurs via inhibition of prostaglandin synthesis an...

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Detalhes bibliográficos
Main Authors: Schoultz, Ida, McKay, Catherine M., Graepel, Rabea, Phan, Van C., Wang, Arthur, Söderholm, Johan, McKay, Derek M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468559/
https://ncbi.nlm.nih.gov/pubmed/22700821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00125.2012
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