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HLA class I binding of mutant EGFR peptides in NSCLC is associated with improved survival
RATIONALE: Cancer-associated mutations have the potential to generate neoantigens and elicit CD8 positive T cell dependent adaptive immune responses. There are currently no reports of CD8 positive T cells with specificity for neoepitopes generated by EGFR mutations, which are driver oncogenes in a s...
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| Publicat a: | J Thorac Oncol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7797166/ https://ncbi.nlm.nih.gov/pubmed/32927123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2020.08.023 |
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