Citrullination only infrequently impacts peptide binding to HLA class II MHC

It has been hypothesized that HLA class II alleles associated with rheumatoid arthritis (RA) preferentially present self-antigens altered by post-translational modification, such as citrullination. To understand the role of citrullination we tested four RA-associated citrullinated epitopes and their...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sidney, John, Becart, Stephane, Zhou, Mimi, Duffy, Karen, Lindvall, Mikaela, Moore, Erin C., Moore, Eugene L., Rao, Tadimeti, Rao, Navin, Nielsen, Morten, Peters, Bjoern, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421785/
https://ncbi.nlm.nih.gov/pubmed/28481943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177140
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