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Mimicry of canonical translation elongation underlies alanine tail synthesis in RQC
Aborted translation produces large ribosomal subunits obstructed with tRNA-linked nascent-chains, which are substrates of Ribosome-associated Quality Control (RQC). Bacterial RqcH, a widely-conserved RQC factor, senses the obstruction and recruits tRNA(Ala(UGC)) to modify nascent-chain C-termini wit...
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| Publicado no: | Mol Cell |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7796892/ https://ncbi.nlm.nih.gov/pubmed/33259811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.11.001 |
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