Alanine Tails Signal Proteolysis in Bacterial Ribosome-Associated Quality Control

In Ribosome-associated Quality Control (RQC), Rqc2/NEMF closely supports the E3 ligase Ltn1/Listerin in promoting ubiquitylation and degradation of aberrant nascent-chains obstructing large (60S) ribosomal subunits—products of ribosome stalling during translation. However, while Ltn1 is eukaryote-sp...

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Publicado no:Cell
Main Authors: Lytvynenko, Iryna, Paternoga, Helge, Thrun, Anna, Balke, Annika, Müller, Tina A., Chiang, Christina H., Nagler, Katja, Tsaprailis, George, Anders, Simon, Bischofs, Ilka, Maupin-Furlow, Julie A., Spahn, Christian M.T., Joazeiro, Claudio A.P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642441/
https://ncbi.nlm.nih.gov/pubmed/31155236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.05.002
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