Chargement en cours...

Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats

Expansions of CAG/CTG trinucleotide repeats in DNA are the cause of at least 17 degenerative human disorders, including Huntington’s Disease. Repeat instability is thought to occur via the formation of intrastrand hairpins during replication, repair, recombination, and transcription though relativel...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Hu, Tianyu, Morten, Michael J., Magennis, Steven W.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794359/
https://ncbi.nlm.nih.gov/pubmed/33420051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20426-3
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!