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Sequence Length Dictates Repeated CAG Folding in Three-Way Junctions
The etiology of a large class of inherited neurological diseases is founded on hairpin structures adopted by repeated DNA sequences, and this folding is determined by base sequence and DNA context. Using single substitutions of adenine with 2-aminopurine, we show that intrastrand folding in repeated...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026861/ https://ncbi.nlm.nih.gov/pubmed/21142085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101756e |
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