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Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
Expansions of CAG/CTG trinucleotide repeats in DNA are the cause of at least 17 degenerative human disorders, including Huntington’s Disease. Repeat instability is thought to occur via the formation of intrastrand hairpins during replication, repair, recombination, and transcription though relativel...
Uloženo v:
| Vydáno v: | Nat Commun |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7794359/ https://ncbi.nlm.nih.gov/pubmed/33420051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20426-3 |
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