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Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy
Guanine rich regions of oligonucleotides fold into quadruple-stranded structures called G-quadruplexes (G4s). Increasing evidence suggests that these G4 structures form in vivo and play a crucial role in cellular processes. However, their direct observation in live cells remains a challenge. Here we...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7794231/ https://ncbi.nlm.nih.gov/pubmed/33420085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20414-7 |
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