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The interactions between a small molecule and G-quadruplexes are visualized by fluorescence lifetime imaging microscopy
Guanine-rich oligonucleotides can fold into quadruple-stranded helical structures known as G-quadruplexes. Mounting experimental evidence has gathered suggesting that these non-canonical nucleic acid structures form in vivo and play essential biological roles. However, to date, there are no small-mo...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4579598/ https://ncbi.nlm.nih.gov/pubmed/26350962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9178 |
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