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The interplay between asymmetric and symmetric DNA loop extrusion

Chromosome compaction is essential for reliable transmission of genetic information. Experiments suggest that ∼1000-fold compaction is driven by condensin complexes that extrude chromatin loops, by progressively collecting chromatin fiber from one or both sides of the complex to form a growing loop....

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Banigan, Edward J, Mirny, Leonid A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793625/
https://ncbi.nlm.nih.gov/pubmed/33295869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63528
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