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Urea-Peptide Hybrids as VEGF-A(165)/NRP-1 Complex Inhibitors with Improved Receptor Affinity and Biological Properties
Neuropilin-1 (NRP-1), the major co-receptor of vascular endothelial growth factor receptor-2 (VEGFR-2), may also independently act with VEGF-A(165) to stimulate tumour growth and metastasis. Therefore, there is great interest in compounds that can block VEGF-A165/NRP-1 interaction. Peptidomimetic ty...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7793531/ https://ncbi.nlm.nih.gov/pubmed/33374715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010072 |
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