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Neuropilin-1 peptide-like ligands with proline mimetics, tested using the improved chemiluminescence affinity detection method

Many reports have suggested that NRP-1 acts as a co-receptor for VEGF-A(165) and boosts tumour growth and metastasis. This NRP-1, due to its important role in tumour progression, triggered interest in the design of new molecules able to significantly inhibit NRP-1/VEGF-A(165) interaction to suppress...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Puszko, Anna K., Sosnowski, Piotr, Tymecka, Dagmara, Raynaud, Françoise, Hermine, Olivier, Lepelletier, Yves, Misicka, Aleksandra
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6390686/
https://ncbi.nlm.nih.gov/pubmed/30881620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00537k
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