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Genetic background and PfKelch13 affect artemisinin susceptibility of PfCoronin mutants in Plasmodium falciparum

Malaria continues to impose a significant health burden in the continent of Africa with 213 million cases in 2018 alone, representing 93% of cases worldwide. Because of high transmission of malaria within the continent, the selection pressures to develop drug resistance in African parasites are dist...

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Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Sharma, Aabha I., Shin, Sara H., Bopp, Selina, Volkman, Sarah K., Hartl, Daniel L., Wirth, Dyann F.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793257/
https://ncbi.nlm.nih.gov/pubmed/33370279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009266
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