Artemisinin resistance without pfkelch13 mutations in Plasmodium falciparum isolates from Cambodia

BACKGROUND: Artemisinin resistance is associated with delayed parasite clearance half-life in vivo and correlates with ring-stage survival under dihydroartemisinin in vitro. Both phenotypes are associated with mutations in the PF3D7_1343700 pfkelch13 gene. Recent spread of artemisinin resistance and...

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Enregistré dans:
Détails bibliographiques
Publié dans:Malar J
Auteurs principaux: Mukherjee, Angana, Bopp, Selina, Magistrado, Pamela, Wong, Wesley, Daniels, Rachel, Demas, Allison, Schaffner, Stephen, Amaratunga, Chanaki, Lim, Pharath, Dhorda, Mehul, Miotto, Olivo, Woodrow, Charles, Ashley, Elizabeth A., Dondorp, Arjen M., White, Nicholas J., Wirth, Dyann, Fairhurst, Rick, Volkman, Sarah K.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427620/
https://ncbi.nlm.nih.gov/pubmed/28494763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1845-5
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