Mutations in Plasmodium falciparum actin-binding protein coronin confer reduced artemisinin susceptibility

Drug resistance is an obstacle to global malaria control, as evidenced by the recent emergence and rapid spread of delayed artemisinin (ART) clearance by mutant forms of the PfKelch13 protein in Southeast Asia. Identifying genetic determinants of ART resistance in African-derived parasites is import...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Demas, Allison R., Sharma, Aabha I., Wong, Wesley, Early, Angela M., Redmond, Seth, Bopp, Selina, Neafsey, Daniel E., Volkman, Sarah K., Hartl, Daniel L., Wirth, Dyann F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2018
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294886/
https://ncbi.nlm.nih.gov/pubmed/30420498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812317115
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