HIV Protease Inhibitor Ritonavir Impairs Endothelial Function Via Reduction in Adipose Mass and Endothelial Leptin Receptor‐Dependent Increases in NADPH Oxidase 1 (Nox1), C‐C Chemokine Receptor Type 5 (CCR5), and Inflammation

BACKGROUND: Cardiovascular disease is currently the leading cause of death in patients with human immunodeficiency virus on combination antiretroviral therapy. Although the use of the protease inhibitor ritonavir has been associated with increased prevalence of cardiovascular disease, the underlying...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Bruder‐Nascimento, Thiago, Kress, Taylor C., Kennard, Simone, Belin de Chantemèle, Eric J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792423/
https://ncbi.nlm.nih.gov/pubmed/33003981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.018074
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