Leptin Restores Endothelial Function via Endothelial PPARγ-Nox1-Mediated Mechanisms in a Mouse Model of Congenital Generalized Lipodystrophy

Leptin is the current treatment for metabolic disorders associated with acquired and congenital generalized lipodystrophy (CGL). Although excess leptin levels have been associated with vascular inflammation and cardiovascular disease in the context of obesity, the effects of chronic leptin treatment...

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Vydáno v:Hypertension
Hlavní autoři: Bruder-Nascimento, Thiago, Faulkner, Jessica L., Haigh, Stephen, Kennard, Simone, Antonova, Galina, Patel, Vijay S., Fulton, David J.R., Chen, Weiqin, de Chantemèle, Eric J. Belin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886673/
https://ncbi.nlm.nih.gov/pubmed/31656096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13398
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