Selective deficiency in endothelial PTP1B protects from diabetes and endoplasmic reticulum stress-associated endothelial dysfunction via preventing endothelial cell apoptosis

Diabetes notably increases the risk for endothelial dysfunction, a main precursor for microvascular complications. While endoplasmic reticulum stress (ERS) and protein tyrosine phosphatase 1B (PTP1B) have been associated with endothelial dysfunction in resistance vessels, whether these mechanisms al...

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Publicado no:Biomed Pharmacother
Main Authors: Legeay, Samuel, Fautrat, Pierre, Norman, J. Blake, Antonova, Galina, Kennard, Simone, Bruder-Nascimento, Thiago, Patel, Vijay S., Faure, Sebastien, de Chantemèle, Eric J. Belin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685223/
https://ncbi.nlm.nih.gov/pubmed/32417688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2020.110200
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