HIV Protease Inhibitor Ritonavir Impairs Endothelial Function Via Reduction in Adipose Mass and Endothelial Leptin Receptor‐Dependent Increases in NADPH Oxidase 1 (Nox1), C‐C Chemokine Receptor Type 5 (CCR5), and Inflammation

BACKGROUND: Cardiovascular disease is currently the leading cause of death in patients with human immunodeficiency virus on combination antiretroviral therapy. Although the use of the protease inhibitor ritonavir has been associated with increased prevalence of cardiovascular disease, the underlying...

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Bibliografski detalji
Izdano u:J Am Heart Assoc
Glavni autori: Bruder‐Nascimento, Thiago, Kress, Taylor C., Kennard, Simone, Belin de Chantemèle, Eric J.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792423/
https://ncbi.nlm.nih.gov/pubmed/33003981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.018074
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