Progesterone predisposes females to obesity-associated leptin-mediated endothelial dysfunction via upregulating endothelial mineralocorticoid receptor expression

Compelling clinical evidence indicates that obesity and its associated metabolic abnormalities supersede the protective effects of female sex-hormones and predisposes premenopausal women to cardiovascular disease. The underlying mechanisms remain poorly defined; however, recent studies have implicat...

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Publicado no:Hypertension
Main Authors: Faulkner, Jessica L., Kennard, Simone, Huby, Anne-Cecile, Antonova, Galina, Lu, Qing, Jaffe, Iris Z., Patel, Vijay S., Fulton, David J.R., de Chantemèle, Eric J. Belin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687552/
https://ncbi.nlm.nih.gov/pubmed/31327274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.12802
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