Nalaganje...

A serine loop in tissue factor mediates substrate selectivity by the tissue factor – factor VIIa complex

BACKGROUND: The tissue factor – factor VIIa (TF-FVIIa) complex is the physiologic activator of blood clotting and plays a major role in many thrombotic diseases. TF-FVIIa drives clotting through proteolytic cleavage of its major protein substrates, factor IX (FIX) and factor X (FX). However, it rema...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Thromb Haemost
Main Authors: Birkle, Fabienne, Morrissey, James H.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790960/
https://ncbi.nlm.nih.gov/pubmed/32885882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15087
Oznake: Označite
Brez oznak, prvi označite!