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Dynamical view of membrane binding and complex formation of human factor VIIa and tissue factor

BACKGROUND: The molecular mechanism of enhancement of the enzymatic activity of factor VIIa (FVIIa) by tissue factor (TF) is not fully understood, primarily due to the lack of atomic models for the membrane-bound form of the TF:FVIIa complex. OBJECTIVES: To construct the first membrane-bound model o...

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Detalhes bibliográficos
Main Authors: Ohkubo, Y Zenmei, Morrissey, James H., Tajkhorshid, Emad
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890040/
https://ncbi.nlm.nih.gov/pubmed/20180816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03826.x
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