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Tissue Factor/Factor VIIa Complex: Role of the Membrane Surface
Blood clotting is triggered when the plasma serine protease factor VIIa binds to the cell-surface protein, tissue factor (TF); the resulting TF:FVIIa complex activates factors IX (FIX) and X (FX) by limited proteolysis. FVIIa, FIX and FX all bind reversibly to membranes via their gamma-carboxyglutam...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335922/ https://ncbi.nlm.nih.gov/pubmed/22417943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2012.02.019 |
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