Tissue Factor/Factor VIIa Complex: Role of the Membrane Surface

Blood clotting is triggered when the plasma serine protease factor VIIa binds to the cell-surface protein, tissue factor (TF); the resulting TF:FVIIa complex activates factors IX (FIX) and X (FX) by limited proteolysis. FVIIa, FIX and FX all bind reversibly to membranes via their gamma-carboxyglutam...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Morrissey, James H., Tajkhorshid, Emad, Sligar, Stephen G., Rienstra, Chad M.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335922/
https://ncbi.nlm.nih.gov/pubmed/22417943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2012.02.019
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki