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Dynamical view of membrane binding and complex formation of human factor VIIa and tissue factor

BACKGROUND: The molecular mechanism of enhancement of the enzymatic activity of factor VIIa (FVIIa) by tissue factor (TF) is not fully understood, primarily due to the lack of atomic models for the membrane-bound form of the TF:FVIIa complex. OBJECTIVES: To construct the first membrane-bound model o...

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Bibliografiska uppgifter
Huvudupphovsmän: Ohkubo, Y Zenmei, Morrissey, James H., Tajkhorshid, Emad
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890040/
https://ncbi.nlm.nih.gov/pubmed/20180816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03826.x
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