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Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
Senescence is the consequence of a signaling mechanism activated in stressed cells to prevent proliferation of cells with damage. Senescent cells (Sncs) often develop a senescence-associated secretory phenotype to prompt immune clearance, which drives chronic sterile inflammation and plays a causal...
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| Publicado no: | Annu Rev Pharmacol Toxicol |
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| Principais autores: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7790861/ https://ncbi.nlm.nih.gov/pubmed/32997601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-050120-105018 |
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