Interplay between UNG and AID governs intratumoral heterogeneity in mature B cell lymphoma

Most B cell lymphomas originate from B cells that have germinal center (GC) experience and bear chromosome translocations and numerous point mutations. GC B cells remodel their immunoglobulin (Ig) genes by somatic hypermutation (SHM) and class switch recombination (CSR) in their Ig genes. Activation...

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Vydáno v:PLoS Genet
Hlavní autoři: Delgado, Pilar, Álvarez-Prado, Ángel F., Marina-Zárate, Ester, Sernandez, Isora V., Mur, Sonia M., de la Barrera, Jorge, Sanchez-Cabo, Fátima, Cañamero, Marta, de Molina, Antonio, Belver, Laura, de Yébenes, Virginia G., Ramiro, Almudena R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790409/
https://ncbi.nlm.nih.gov/pubmed/33362210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008960
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