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Interplay between UNG and AID governs intratumoral heterogeneity in mature B cell lymphoma
Most B cell lymphomas originate from B cells that have germinal center (GC) experience and bear chromosome translocations and numerous point mutations. GC B cells remodel their immunoglobulin (Ig) genes by somatic hypermutation (SHM) and class switch recombination (CSR) in their Ig genes. Activation...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7790409/ https://ncbi.nlm.nih.gov/pubmed/33362210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008960 |
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