AID-expressing epithelium is protected from oncogenic transformation by an NKG2D surveillance pathway

Activation-induced deaminase (AID) initiates secondary antibody diversification in germinal center B cells, giving rise to higher affinity antibodies through somatic hypermutation (SHM) or to isotype-switched antibodies through class switch recombination (CSR). SHM and CSR are triggered by AID-media...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Pérez-García, Arantxa, Pérez-Durán, Pablo, Wossning, Thomas, Sernandez, Isora V, Mur, Sonia M, Cañamero, Marta, Real, Francisco X, Ramiro, Almudena R
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604686/
https://ncbi.nlm.nih.gov/pubmed/26282919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505348
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