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microRNAs prevent the generation of autoreactive antibodies

MicroRNAs have been shown critical for a number of aspects of immune system regulation and function. Here we have examined the role of microRNAs in terminal B cell differentiation by analysing Cd19-Cre(ki/+) Dicer(fl/fl) mice. We found that in the absence of Dicer the transitional and marginal zone...

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Main Authors: Belver, Laura, de Yébenes, Virginia G, Ramiro, Almudena R
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687137/
https://ncbi.nlm.nih.gov/pubmed/21093320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.11.010
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