Extracellular vesicles released from the filarial parasite Brugia malayi downregulate the host mTOR pathway

We have previously shown that the microfilarial (mf) stage of Brugia malayi can inhibit the mammalian target of rapamycin (mTOR; a conserved serine/threonine kinase critical for immune regulation and cellular growth) in human dendritic cells (DC) and we have proposed that this mTOR inhibition is ass...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Negl Trop Dis
Egile Nagusiak: Ricciardi, Alessandra, Bennuru, Sasisekhar, Tariq, Sameha, Kaur, Sukhbir, Wu, Weiwei, Elkahloun, Abdel G., Arakelyan, Anush, Shaik, Jahangheer, Dorward, David W., Nutman, Thomas B., Tolouei Semnani, Roshanak
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2021
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790274/
https://ncbi.nlm.nih.gov/pubmed/33411714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008884
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