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Extracellular vesicles released from the filarial parasite Brugia malayi downregulate the host mTOR pathway
We have previously shown that the microfilarial (mf) stage of Brugia malayi can inhibit the mammalian target of rapamycin (mTOR; a conserved serine/threonine kinase critical for immune regulation and cellular growth) in human dendritic cells (DC) and we have proposed that this mTOR inhibition is ass...
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| 出版年: | PLoS Negl Trop Dis |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7790274/ https://ncbi.nlm.nih.gov/pubmed/33411714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008884 |
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