Extracellular vesicles released from the filarial parasite Brugia malayi downregulate the host mTOR pathway

We have previously shown that the microfilarial (mf) stage of Brugia malayi can inhibit the mammalian target of rapamycin (mTOR; a conserved serine/threonine kinase critical for immune regulation and cellular growth) in human dendritic cells (DC) and we have proposed that this mTOR inhibition is ass...

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Опубликовано в: :PLoS Negl Trop Dis
Главные авторы: Ricciardi, Alessandra, Bennuru, Sasisekhar, Tariq, Sameha, Kaur, Sukhbir, Wu, Weiwei, Elkahloun, Abdel G., Arakelyan, Anush, Shaik, Jahangheer, Dorward, David W., Nutman, Thomas B., Tolouei Semnani, Roshanak
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2021
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790274/
https://ncbi.nlm.nih.gov/pubmed/33411714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008884
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