Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy

BACKGROUND: Immunotherapy with checkpoint inhibitors has shown impressive results in patients with melanoma, but still many do not benefit from this line of treatment. A lack of tumor-infiltrating T cells is a common reason for therapy failure but also a loss of intratumoral dendritic cells (DCs) ha...

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書目詳細資料
發表在:J Immunother Cancer
Main Authors: Prokopi, Anastasia, Tripp, Christoph H, Tummers, Bart, Hornsteiner, Florian, Spoeck, Sarah, Crawford, Jeremy Chase, Clements, Derek R, Efremova, Mirjana, Hutter, Katharina, Bellmann, Lydia, Cappellano, Giuseppe, Cadilha, Bruno L, Kobold, Sebastian, Boon, Louis, Ortner, Daniela, Trajanoski, Zlatko, Chen, Suzie, de Gruijl, Tanja D, Idoyaga, Juliana, Green, Douglas R, Stoitzner, Patrizia
格式: Artigo
語言:Inglês
出版: BMJ Publishing Group 2021
主題:
Immune Cell Therapies and Immune Cell Engineering
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789456/
https://ncbi.nlm.nih.gov/pubmed/33408092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000832
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