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Neoantigens Generated by Individual Mutations and Their Role in Cancer Immunity and Immunotherapy

Recent preclinical and clinical studies have proved the long-standing hypothesis that tumors elicit adaptive immune responses and that the antigens driving effective T-cell response are neoantigens, i.e., peptides that are generated from somatically mutated genes. Hence, the characterization of neoa...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Efremova, Mirjana, Finotello, Francesca, Rieder, Dietmar, Trajanoski, Zlatko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712389/
https://ncbi.nlm.nih.gov/pubmed/29234329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01679
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