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New strategies for cancer immunotherapy: targeting regulatory T cells

The immunosuppressive action of regulatory T (T(reg)) cells is one mechanism attributed to the limited success of cancer immunotherapies with checkpoint blockers. Two recent studies report distinct transcriptional profiles of tumor-infiltrating T(reg) cells and expression of specific molecules, sugg...

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Détails bibliographiques
Publié dans:Genome Med
Auteurs principaux: Finotello, Francesca, Trajanoski, Zlatko
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5273791/
https://ncbi.nlm.nih.gov/pubmed/28129791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0402-8
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