NeoFuse: predicting fusion neoantigens from RNA sequencing data

SUMMARY: Gene fusions can generate immunogenic neoantigens that mediate anticancer immune responses. However, their computational prediction from RNA sequencing (RNA-seq) data requires deep bioinformatics expertise to assembly a computational workflow covering the prediction of: fusion transcripts,...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Fotakis, Georgios, Rieder, Dietmar, Haider, Marlene, Trajanoski, Zlatko, Finotello, Francesca
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Applications Notes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141848/
https://ncbi.nlm.nih.gov/pubmed/31755900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz879
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