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Germline variants are associated with increased primary melanoma tumor thickness at diagnosis

Germline genetic variants have been identified, which predispose individuals and families to develop melanoma. Tumor thickness is the strongest predictor of outcome for clinically localized primary melanoma patients. We sought to determine whether there is a heritable genetic contribution to variati...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Mangantig, Ernest, MacGregor, Stuart, Iles, Mark M, Scolyer, Richard A, Cust, Anne E, Hayward, Nicholas K, Montgomery, Grant W, Duffy, David L, Thompson, John F, Henders, Anjali, Bowdler, Lisa, Rowe, Casey, Cadby, Gemma, Mann, Graham J, Whiteman, David C, Long, Georgina V, Ward, Sarah V, Khosrotehrani, Kiarash, Barrett, Jennifer H, Law, Matthew H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788289/
https://ncbi.nlm.nih.gov/pubmed/33410475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa222
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